Poly-N-isopropylacrylamide (pNIPAM): a reversible bioadhesive for sclerotomy closure
نویسندگان
چکیده
منابع مشابه
Poly-N-isopropylacrylamide (pNIPAM): a reversible bioadhesive for sclerotomy closure
PURPOSE To determine the safety and efficacy of poly-N-isopropylacrylamide, a thermoresponsive adhesive, for sutureless sclerotomy closure in rabbits. METHODS Eight rabbits were randomized into three groups: short-term acute, mid-term chronic, and long-term chronic studies. A corresponding control group in which the scleral wounds were sutured by 6-0 vicryl sutures was assigned for each study...
متن کاملOcular Biocompatibility of Poly-N-Isopropylacrylamide (pNIPAM)
Purpose. To study the safety of intravitreal injections of poly-N-isopropylacrylamide (pNIPAM) tissue adhesive in rabbit eyes. Methods. Twelve study rabbits received an intravitreal injection of 0.1 mL 50% pNIPAM in the right eye. Follow-up examinations included color fundus photography, fundus fluorescein angiography (FA), optical coherence tomography (OCT), and electroretinography (ERG). Subs...
متن کاملEffect of Poly (n-isopropylacrylamide) “pnipam” on Hepatic Cells of Swiss Albino Mice, Mus Musculus
The present paper deals with the effect of polymeric compound poly (N-isopropyl acrylamide) “PNIPAM” for their toxicity on hepatic cells. The nanoparticle is a xenobiotic compound that accumulates in the liver for their metabolism. Non-metabolizing xenobiotic compounds such as “PNIPAM” produces anomalies in the hepatic cells. Certain enzymes such as ALT and ALP can be assayed for the hepatocyti...
متن کاملThe Importance of Excess Poly(N-isopropylacrylamide) for the Aggregation of Poly(N-isopropylacrylamide)-Coated Gold Nanoparticles.
Thermoresponsive materials are generating significant interest on account of the sharp and tunable temperature deswelling transition of the polymer chain. Such materials have shown promise in drug delivery devices, sensing systems, and self-assembly. Incorporation of nanoparticles (NPs), typically through covalent attachment of the polymer chains to the NP surface, can add additional functional...
متن کاملReversible switching of substrate activity of poly-N-isopropylacrylamide peptide conjugates.
The activity of smart polymer peptide conjugates towards chymotrypsin catalyzed hydrolysis was reversibly switched on and off using temperature as the trigger.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Retina and Vitreous
سال: 2016
ISSN: 2056-9920
DOI: 10.1186/s40942-016-0048-5